HOME ABOUT US CONTACT

Hepatitis B Vaccine Adverse Reactions Reported in the Medical Literature

The below list includes reports of adverse reactions linked to the hepatitis B vaccine that have been reported in the medical literature. The list is by no means complete.

Blood Disorders

  • Ashok Shenoy K, Prabha Adhikari MR, Chakrapani M, Shenoy D, Pillai A. Pancytopenia after recombinant hepatitis B vaccine--an Indian case report. Br J Haematol. 2001 Sep;114(4):955. PMID: 11564093
  • Conesa V, Nunez Mf, Navarro JF, Mompel A, Ruiz J, Gomez A. Thrombocytopenic Purpura after Recombinant Hepatitis B Vaccine. A rare association. Haematologica. 2001 Mar;86(3):E09. No abstract available. PMID: 11255296
  • Lliminana C, Soler JA, Melo M, Roig I. [Hemolytic anemia and thrombocytopenic purpura after the administration of the recombinant hepatitis B vaccine] Med Clin (Barc). 1999 Jun 12;113(1):39. Spanish. PMID: 10422080
  • Muller A, Kertzscher F, Kiefel V, Lenk H. Thrombocytopenic purpura: adverse reaction to a combined immunisation (recombinant hepatitis B and measles-mumps-rubella-vaccine) and after therapy with Co-trimoxazole. Eur J Pediatr. 1999 Dec;158 Suppl 3:S209-10. No abstract available. PMID: 10650872
  • Neau D, Bonnet F, Michaud M, Perel Y, Longy-Boursier M, Ragnaud JM, Guillard JM. Immune thrombocytopenic purpura after recombinant hepatitis B vaccine: retrospective study of seven cases. Scand J Infect Dis. 1998;30(2):115-8. PMID: 9730294
  • Ronchi F, Cecchi P, Falcioni F, Marsciani A, Minak G, Muratori G, Tazzari PL, Beverini S. Thrombocytopenic purpura as adverse reaction to recombinant hepatitis B vaccine. Arch Dis Child. 1998 Mar;78(3):273-4. PMID: 9613364
  • Poullin P, Gabriel B. Thrombocytopenic purpura after recombinant hepatitis B vaccine. Lancet. 1994 Nov 5;344(8932):1293. No abstract available. PMID: 7967998

    • Guillain-Barre Syndrome

  • Kakar A, Sethi PK., Guillain Barre syndrome associated with hepatitis B vaccination. Indian J Pediatr. 1997 Sep-Oct;64(5):710-2. No abstract available. PMID: 10771907
  • Sindern E, Schroder JM, Krismann M, Malin JP. Inflammatory polyradiculoneuropathy with spinal cord involvement and lethal [correction of letal] outcome after hepatitis B vaccination. J Neurol Sci. 2001 May 1;186(1-2):81-5. PMID: 11412876
  • Sinsawaiwong S, Thampanitchawong P., Guillain - Barre' syndrome following recombinant hepatitis B vaccine and literature review., J Med Assoc Thai. 2000 Sep;83(9):1124-6. Review. PMID: 11075984
  • Tuohy PG., Guillain-Barre syndrome following immunisation with synthetic hepatitis B vaccine. N Z Med J. 1989 Mar 8;102(863):114-5. PMID: 2522608
  • Wu Z, Wu H, Wang Q, et Al., [A Case-control Study on Guillain-Barre Syndrome in Children of North China], Zhonghua Yu Fang Yi Xue Za Zhi. 1999 Sep;33(5):279-81. Chinese. PMID: 11864491

    • Respiratory Failure

  • Becker BA, A Severe Allergic Reaction Presenting as an Asthma Exacerbation With Respiratory Failure Following Hepatitis B Vaccination. Journal of Allergy and Clinical Immunology. 2002 Jan; 109(1) Part Two

    • Rheumatic Disorders

  • Biasi D, De Sandre G, Bambara LM, Carletto A, Caramaschi P, Zanoni G, Tridente G. A new case of reactive arthritis after hepatitis B vaccination. Clin Exp Rheumatol. 1993 Mar-Apr;11(2):215. No abstract available. PMID: 8508565
  • Biasi D, Carletto A, Caramaschi P, Frigo A, Pacor ML, Bezzi D, Bambara LM. [Rheumatological manifestations following hepatitis B vaccination. A report of 2 clinical cases] Recenti Prog Med. 1994 Sep;85(9):438-40. Review. Italian. PMID: 7938876
  • Bracci M, Zoppini A. Polyarthritis associated with hepatitis B vaccination. Br J Rheumatol. 1997 Feb;36(2):300-1. No abstract available. PMID: 9133957

    • Vasculitis

  • Allen MB, Cockwell P, Page RL. Pulmonary and cutaneous vasculitis following hepatitis B vaccination. Thorax. 1993 May;48(5):580-1. No abstract available. PMID: 8322254
  • Beretta L, Caronni M, Vanoli M, Scorza R. Churg-Strauss vasculitis with brain involvement following hepatitis B vaccination. Clin Exp Rheumatol. 2001 Nov-Dec;19(6):757. No abstract available. PMID: 11791655
  • Bui-Quang D, Thomas E, Riols M, Levillain P, Picaud D, Sechet A, Baron M, Verove C. [Cutaneous vasculitis after hepatitis B vaccination with recombinant vaccine in a renal transplant patient] Presse Med. 1998 Sep 12;27(26):1321-3. French. PMID: 9779046
  • Castresana-Isla CJ, Herrera-Martinez G, Vega-Molina J. Erythema nodosum and Takayasu's arteritis after immunization with plasma derived hepatitis B vaccine. J Rheumatol. 1993 Aug;20(8):1417-8. PMID: 7901414

    • Vision Loss

  • Albitar S, Bourgeon B, Genin R, Fen-Chong M, N'Guyen P, Serveaux MO, Atchia H, Schohn D., Bilateral retrobulbar optic neuritis with hepatitis B vaccination. Nephrol Dial Transplant. 1997 Oct;12(10):2169-70. No abstract available. PMID: 9351086
  • Arya SC. Ophthalmic complications of vaccines against hepatitis B virus. Int Ophthalmol. 1997;21(3):177-8. No abstract available. PMID: 9587836
  • Berkman N, Benzarti T, Dhaoui R, Mouly P. [Bilateral neuro-papillitis after hepatitis B vaccination] Presse Med. 1996 Sep 28;25(28):1301. French. No abstract available. PMID: 8949792
  • Bourges JL, Pisella PJ, Laurens C, Limon S. [Multifocal placoid epitheliopathy and anti-hepatitis B vaccination] J Fr Ophtalmol. 1998 Nov;21(9):696-700. French. PMID: 9894208
  • Brezin AP, Massin-Korobelnik P, Boudin M, Gaudric A, LeHoang P. Acute posterior multifocal placoid pigment epitheliopathy after hepatitis B vaccine. Arch Ophthalmol. 1995 Mar;113(3):297-300. PMID: 7887843
  • Brezin A, Lautier-Frau M, Hamedani M, Rogeaux O, Hoang PL. Visual loss and eosinophilia after recombinant hepatitis B vaccine. Lancet. 1993 Aug 28;342(8870):563-4. No abstract available. PMID: 8102709