Presse Med 1998 Sep 12;27(26):1321-3

[Cutaneous vasculitis after hepatitis B vaccination with recombinant vaccine in a renal transplant patient]

[Article in French]
Bui-Quang D, Thomas E, Riols M, Levillain P, Picaud D, Sechet A, Baron M, Verove C.
Service de Nephrologie-Hemodialyse, Centre Hospitalier, Niort.

BACKGROUND: Cutaneous vasculitis is a known complication of hepatitis B vaccination with recombinant vaccine. CASE REPORT: A renal transplant recipient with the HLD-DR4 susceptibility antigen developed histologically proven cutaneous vasculitis with serum antibodies after vaccination with anti-hepatitis B recombinant vaccine. The skin manifestation, evolved favorably after discontinuation of the immunization and bed rest. DISCUSSION: This case suggests that anti-hepatitis B vaccination with recombinant vaccine can produce cutaneous vasculitis in renal transplant recipients. The vaccination strategy in this population should be revisited.

PMID: 9779046